I'm left handed, there are some things you just have to live with.
- The handle for the pillar drill is on the wrong side, as are all the clamps.
- Jigsaws, routers etc can be fiddly.
- Grinders with the switch on the side are a PITA.
Of course, there are times when it's an advantage, i was helping my dad build some shuttering this weekend, he's right handed so between us we were comfortable able to swing a hammer into all the corners we needed to etc.